How can I "install" and use Orfeo Toolbox (OTB) through python 3.6 (NO Conda)?

Using Python v.3.6.8 through Jupiter notebook (in Windows 10), how can I set and use OTB (v.7.3.0)? I followed the steps described in the official cookbook and other tutorials, however, the result is:

No module named 'otbApplication'

Many people encounter the same problem. Could anyone who has already solved this problem describe the various steps (starting from scratch) once and for all, please?
The community would be grateful.